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Orriols, R., Costa, R., Cuberas, G., Jacas, C., Castell, J., Sunyer, J.

Brain dysfunction in multiple chemical sensitivity

J.Neurol.Sci., 2009, 287, 1, 72, 78, IF: 2.324, PMID: 19801154

Multiple Chemical Sensitivity (MCS) is a chronic acquired disorder of unknown pathogenesis. The aim of this study was to ascertain whether MCS patients present brain single photon emission computed tomography (SPECT) and psychometric scale changes after a chemical challenge. This procedure was performed with chemical products at non-toxic concentrations in 8 patients diagnosed with MCS and in their healthy controls. In comparison to controls, cases presented basal brain SPECT hypoperfusion in small cortical areas of the right parietal and both temporal and fronto-orbital lobes. After chemical challenge, cases showed hypoperfusion in the olfactory, right and left hippocampus, right parahippocampus, right amygdala, right thalamus, right and left Rolandic and right temporal cortex regions(p

CLINICAL NEUROLOGY, NEUROSCIENCES


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