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Risk of preeclampsia associated with exposure to fine particulate air pollution

Published in Environmental Health Perspectives

Friday, September 27th, 2013

Risk of preeclampsia associated with exposure to fine particulate air pollution

Researchers at the Centre for Research in Environmental Epidemiology (CREAL), centre of the ISGlobal alliance, found an increased risk of preeclampsia associated with exposure to fine particulate air pollution.  This study was published in Environmental Health Perspectives

The preaclampsia is a life-threatening disorder that occurs only during pregnancy period. Preeclampsia is often characterized by a rapid rise in blood pressure that can lead to seizure, stroke, multiple organ failure and death of the mother and/or baby.

The objective of this study was investigate the association between preeclampsia and exposure to air pollution (NO2, NOx, PM) during the entire pregnancy, and during the first, second, and third trimesters. The researchers have observed an increased risk of preeclampsia associated with exposure to fine particulate air pollution. 

The researchers have found positive associations for most of their evaluated outcome-exposure pairs with the strongest associations observed for preeclampsia and late-onset preeclampsia in relation with the third trimester exposure to fine particulate pollutants and for early-onset preeclampsia in relation with the first trimester exposure to fine particulate pollutants. “Among the investigated associations, those of the first and third trimester exposures to PM2.5 and the third trimester exposure to PM2.5 absorbance and preeclampsia and the third trimester PM2.5 exposure and late-onset preeclampsia attained statistical significance”, explains Payam Dadvand, main researcher of this study that was based on 8,398 pregnancies (including 103 cases of preeclampsia) among women residing in Barcelona (2000-2005). 

Reference

Dadvand P, FiguerasF, Basagaña X, Beelen R, Martinez D, Cirach M, Schembari A, Hoek G, Brunekreef B, Nieuwenhuijsen MJ. Ambient Air Pollution and Preeclampsia: A Spatiotemporal Analysis. Environ Health Perspect. 2013 Sep 10.


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